A weighted HP model for protein folding with diagonal contacts
The HP model is one of the most popular discretized models for attacking the protein folding problem, , for the computational prediction of the tertiary structure of a protein from its amino acid sequence. It is based on the assumption that interactions between hydrophobic amino acids are the main force in the folding process. Therefore, it distinguishes between polar and hydrophobic amino acids only and tries to embed the amino acid sequence into a two- or three-dimensional grid lattice such...