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Rapid Emergence of Co-colonization with Community-acquired and Hospital-Acquired Methicillin-Resistant Strains in the Hospital Setting

E. M. C. D’AgataG. F. WebbJ. Pressley — 2010

Mathematical Modelling of Natural Phenomena

Background: Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA), a novel strain of MRSA, has recently emerged and rapidly spread in the community. Invasion into the hospital setting with replacement of the hospital-acquired MRSA (HA-MRSA) has also been documented. Co-colonization with both CA-MRSA and HA-MRSA would have important clinical implications given differences in ...

Global Existence and Boundedness of Solutions to a Model of Chemotaxis

J. DysonR. Villella-BressanG. F. Webb — 2008

Mathematical Modelling of Natural Phenomena

A model of chemotaxis is analyzed that prevents blow-up of solutions. The model consists of a system of nonlinear partial differential equations for the spatial population density of a species and the spatial concentration of a chemoattractant in -dimensional space. We prove the existence of solutions, which exist globally, and are -bounded on finite time intervals. The hypotheses require nonlocal conditions on the species-induced production of the chemoattractant.

Pre-symptomatic Influenza Transmission, Surveillance, and School Closings: Implications for Novel Influenza A (H1N1)

G. F. WebbY-H. HsiehJ. WuM. J. Blaser — 2010

Mathematical Modelling of Natural Phenomena

Early studies of the novel swine-origin 2009 influenza A (H1N1) epidemic indicate clinical attack rates in children much higher than in adults. Non-medical interventions such as school closings are constrained by their large socio-economic costs. Here we develop a mathematical model to ascertain the roles of pre-symptomatic influenza transmission as well as symptoms surveillance of children to assess the utility of school closures. Our model analysis...

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