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Modeling Spatial Effects in Early Carcinogenesis : Stochastic Versus Deterministic Reaction-Diffusion Systems

R. BertolussoM. Kimmel — 2012

Mathematical Modelling of Natural Phenomena

We consider the early carcinogenesis model originally proposed as a deterministic reaction-diffusion system. The model has been conceived to explore the spatial effects stemming from growth regulation of pre-cancerous cells by diffusing growth factor molecules. The model exhibited Turing instability producing transient spatial spikes in cell density, which might be considered a model counterpart of emerging foci of malignant cells. However, the process...

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