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A Knot Polynomial Invariant for Analysis of Topology of RNA Stems and Protein Disulfide Bonds

Wei TianXue LeiLouis H. KauffmanJie Liang — 2017

Molecular Based Mathematical Biology

Knot polynomials have been used to detect and classify knots in biomolecules. Computation of knot polynomials in DNA and protein molecules have revealed the existence of knotted structures, and provided important insight into their topological structures. However, conventional knot polynomials are not well suited to study RNA molecules, as RNA structures are determined by stem regions which are not taken into account in conventional knot polynomials. In this study, we develop a new class of knot...

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