Diagnostics of the AML with immunophenotypical data

A. Plesa; G. Ciuperca; V. Louvet; L. Pujo-Menjouet; S. Génieys; C. Dumontet; X. Thomas; V. Volpert

Mathematical Modelling of Natural Phenomena (2010)

  • Volume: 1, Issue: 2, page 104-123
  • ISSN: 0973-5348

Abstract

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Patients with acute myeloblastic leukemia (AML) are divided according to the French American British (FAB) classification into eight subgroups (M0 to M7) on the basis of their degree of maturation/differentiation. However, even if immunophenotypical characterization by flow cytometry is routinely used to distinguish between AML and acute lymphoblastic leukemia (ALL), it is not yet well established for the identification within the AML subgroups. Here we show that certain subgroups of AML can be identified with a good accuracy (80% of the patients we analyzed) by means of the expression of specific markers.

How to cite

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Plesa, A., et al. "Diagnostics of the AML with immunophenotypical data." Mathematical Modelling of Natural Phenomena 1.2 (2010): 104-123. <http://eudml.org/doc/222392>.

@article{Plesa2010,
abstract = { Patients with acute myeloblastic leukemia (AML) are divided according to the French American British (FAB) classification into eight subgroups (M0 to M7) on the basis of their degree of maturation/differentiation. However, even if immunophenotypical characterization by flow cytometry is routinely used to distinguish between AML and acute lymphoblastic leukemia (ALL), it is not yet well established for the identification within the AML subgroups. Here we show that certain subgroups of AML can be identified with a good accuracy (80% of the patients we analyzed) by means of the expression of specific markers. },
author = {Plesa, A., Ciuperca, G., Louvet, V., Pujo-Menjouet, L., Génieys, S., Dumontet, C., Thomas, X., Volpert, V.},
journal = {Mathematical Modelling of Natural Phenomena},
keywords = {acute myeloblastic leukemia; diagnostic; FAB classification ; cell markers; mathematical modelling},
language = {eng},
month = {3},
number = {2},
pages = {104-123},
publisher = {EDP Sciences},
title = {Diagnostics of the AML with immunophenotypical data},
url = {http://eudml.org/doc/222392},
volume = {1},
year = {2010},
}

TY - JOUR
AU - Plesa, A.
AU - Ciuperca, G.
AU - Louvet, V.
AU - Pujo-Menjouet, L.
AU - Génieys, S.
AU - Dumontet, C.
AU - Thomas, X.
AU - Volpert, V.
TI - Diagnostics of the AML with immunophenotypical data
JO - Mathematical Modelling of Natural Phenomena
DA - 2010/3//
PB - EDP Sciences
VL - 1
IS - 2
SP - 104
EP - 123
AB - Patients with acute myeloblastic leukemia (AML) are divided according to the French American British (FAB) classification into eight subgroups (M0 to M7) on the basis of their degree of maturation/differentiation. However, even if immunophenotypical characterization by flow cytometry is routinely used to distinguish between AML and acute lymphoblastic leukemia (ALL), it is not yet well established for the identification within the AML subgroups. Here we show that certain subgroups of AML can be identified with a good accuracy (80% of the patients we analyzed) by means of the expression of specific markers.
LA - eng
KW - acute myeloblastic leukemia; diagnostic; FAB classification ; cell markers; mathematical modelling
UR - http://eudml.org/doc/222392
ER -

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