Genetic and Tabu search algorithms for peptide assembly problem
Jacek Błażewicz; Marcin Borowski; Piotr Formanowicz; Tomasz Głowacki
RAIRO - Operations Research (2010)
- Volume: 44, Issue: 2, page 153-166
- ISSN: 0399-0559
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topBłażewicz, Jacek, et al. "Genetic and Tabu search algorithms for peptide assembly problem." RAIRO - Operations Research 44.2 (2010): 153-166. <http://eudml.org/doc/250837>.
@article{Błażewicz2010,
abstract = {
Determining amino acid sequences of protein molecules is one of the most important issues in molecular biology. These
sequences determine protein structure and functionality. Unfortunately, direct biochemical methods for reading amino
acid sequences can be used for reading short sequences only. This is the reason, which makes peptide assembly algorithms
an important complement of these methods. In this paper, a genetic algorithm solving the problem of short amino acid sequence
assembly is presented. The algorithm has been tested in computational experiment and compared with an existing tabu search method
for the same problem. The results clearly show that the genetic algorithm outperformed the tabu search approach.
},
author = {Błażewicz, Jacek, Borowski, Marcin, Formanowicz, Piotr, Głowacki, Tomasz},
journal = {RAIRO - Operations Research},
keywords = {Peptide sequencing; combinatorial optimization problem; genetic algorithm; tabu search algorithm; peptide sequencing},
language = {eng},
month = {4},
number = {2},
pages = {153-166},
publisher = {EDP Sciences},
title = {Genetic and Tabu search algorithms for peptide assembly problem},
url = {http://eudml.org/doc/250837},
volume = {44},
year = {2010},
}
TY - JOUR
AU - Błażewicz, Jacek
AU - Borowski, Marcin
AU - Formanowicz, Piotr
AU - Głowacki, Tomasz
TI - Genetic and Tabu search algorithms for peptide assembly problem
JO - RAIRO - Operations Research
DA - 2010/4//
PB - EDP Sciences
VL - 44
IS - 2
SP - 153
EP - 166
AB -
Determining amino acid sequences of protein molecules is one of the most important issues in molecular biology. These
sequences determine protein structure and functionality. Unfortunately, direct biochemical methods for reading amino
acid sequences can be used for reading short sequences only. This is the reason, which makes peptide assembly algorithms
an important complement of these methods. In this paper, a genetic algorithm solving the problem of short amino acid sequence
assembly is presented. The algorithm has been tested in computational experiment and compared with an existing tabu search method
for the same problem. The results clearly show that the genetic algorithm outperformed the tabu search approach.
LA - eng
KW - Peptide sequencing; combinatorial optimization problem; genetic algorithm; tabu search algorithm; peptide sequencing
UR - http://eudml.org/doc/250837
ER -
References
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