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Studio autoradiografico della distribuzione della bilirubina-3 H in ratti normali o con il coledoco legato

Mario Sposito; Bruno Bertolini; Mario Buongiorno-Nardelli; Giorgio Hassan; Giovanni Marinucci; Roberto Picardi

Atti della Accademia Nazionale dei Lincei. Classe di Scienze Fisiche, Matematiche e Naturali. Rendiconti (1973)

  • Volume: 54, Issue: 6, page 985-990
  • ISSN: 0392-7881

Abstract

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The histological study of intracellular transport and storage of bilirubin was carried out using the autoradiographic technique. 3 H-Bilirubin, prepared accordingto Grodsky's procedure, was injected into normal and obstructed rats. Percent of isotope loss in fixation and dehydration media was calculated and was found low enough on the whole not to impair the significance of the autoradiographic results. Autoradiographs of normal liver showed no definitive intracellular isotope polarization; in the liver of obstructed rats an accumulation of isotope in Kupffer cells was observed. In the kidney of obstructed rats a high concentration of 3 H-Bilirubin was observed in the epithelial cells of second order tubules.

How to cite

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Sposito, Mario, et al. "Studio autoradiografico della distribuzione della bilirubina-3 H in ratti normali o con il coledoco legato." Atti della Accademia Nazionale dei Lincei. Classe di Scienze Fisiche, Matematiche e Naturali. Rendiconti 54.6 (1973): 985-990. <http://eudml.org/doc/293905>.

@article{Sposito1973,
author = {Sposito, Mario, Bertolini, Bruno, Buongiorno-Nardelli, Mario, Hassan, Giorgio, Marinucci, Giovanni, Picardi, Roberto},
journal = {Atti della Accademia Nazionale dei Lincei. Classe di Scienze Fisiche, Matematiche e Naturali. Rendiconti},
language = {ita},
number = {6},
pages = {985-990},
publisher = {Accademia Nazionale dei Lincei},
title = {Studio autoradiografico della distribuzione della bilirubina-3 H in ratti normali o con il coledoco legato},
url = {http://eudml.org/doc/293905},
volume = {54},
year = {1973},
}

TY - JOUR
AU - Sposito, Mario
AU - Bertolini, Bruno
AU - Buongiorno-Nardelli, Mario
AU - Hassan, Giorgio
AU - Marinucci, Giovanni
AU - Picardi, Roberto
TI - Studio autoradiografico della distribuzione della bilirubina-3 H in ratti normali o con il coledoco legato
JO - Atti della Accademia Nazionale dei Lincei. Classe di Scienze Fisiche, Matematiche e Naturali. Rendiconti
PY - 1973
PB - Accademia Nazionale dei Lincei
VL - 54
IS - 6
SP - 985
EP - 990
LA - ita
UR - http://eudml.org/doc/293905
ER -

References

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  3. DE GROOTE, J., FEVERY, J. e HEIRWEGH, K., in Bilirubin Metabolism. Oxford, Blackwell Scientific Publications, 1967. 
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  6. EBERLEIN, W. R., «Pediatrics», 25, 878 (1960). 
  7. GRODSKY, G. M., CARBONE, J. V., FANSKA, R. e PENG, C. T., «Am. J. Physiol.», 203, 532 (1962). 
  8. MAGGIORE, Q., CARTER, M. e BILLING, B. H., «Boll. Soc. It. Biol. Sper.», 39, 941 (1963). 
  9. MILLONING, G., «J. Appl. Physiol.», 32, 1640 (1961). 
  10. NIZET, E. e BARAC, G., «C. R. Soc. Biol. (Paris)», 146, 1282 (1962). 
  11. OKOLICSANY, L., MANGENANT, P. e FREI, J., «Lancet», 1173 (1958). 
  12. OWENE, E., in Bilirubin Metabolism, Oxford, Blackwell Scientific Publications, 1967. 
  13. RAIA, S., ivi. 

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