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Quality improvement of rule-based gene group descriptions using information about GO terms importance occurring in premises of determined rules

Marek SikoraAleksandra Gruca — 2010

International Journal of Applied Mathematics and Computer Science

In this paper we present a method for evaluating the importance of GO terms which compose multi-attribute rules. The rules are generated for the purpose of biological interpretation of gene groups. Each multi-attribute rule is a combination of GO terms and, based on relationships among them, one can obtain a functional description of gene groups. We present a method which allows evaluating the influence of a given GO term on the quality of a rule and the quality of a whole set of rules. For each...

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