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We apply general Hardy type inequalities, recently obtained by the author. As a consequence we obtain a family of Hardy-Poincaré inequalities with certain constants, contributing to the question about precise constants in such inequalities posed in [3]. We confirm optimality of some constants obtained in [3] and [8]. Furthermore, we give constants for generalized inequalities with the proof of their optimality.
We propose a model of vascular tumour growth, which generalises the well recognised model formulated by Hahnfeldt et al. in 1999. Our model is based on the same idea that the carrying capacity for any solid tumour depends on its vessel density but it also incorporates vasculature quality which may be lost during angiogenesis as recognised by Jain in 2005. In the model we assume that the loss of vessel quality affects the diffusion coefficient inside the tumour. We analyse basic mathematical properties...
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