Unbiased group-wise alignment by iterative central tendency estimations
This paper introduces a new approach for the joint alignment of a large collection of segmented images into the same system of coordinates while estimating at the same time an optimal common coordinate system. The atlas resulting from our group-wise alignment algorithm is obtained as the hidden variable of an Expectation-Maximization (EM) estimation. This is achieved by identifying the most consistent label across the collection of images at each voxel in the common frame of coordinates. In an...