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Analysis of the Growth Control Network Specific for Human Lung Adenocarcinoma Cells

G. Pinna; A. Zinovyev; N. Araujo; N. Morozova; A. Harel-Bellan — 2012

Mathematical Modelling of Natural Phenomena

Many cancer-associated genes and pathways remain to be identified in order to clarify the molecular mechanisms underlying cancer progression. In this area, genome-wide loss-of-function screens appear to be powerful biological tools, allowing the accumulation of large amounts of data. However, this approach currently lacks analytical tools to exploit the data with maximum efficiency, for which systems biology methods analyzing complex cellular networks...

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