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The x-ray microanalysis in the transmission electron microscope of different types of tumours (epithelial or not) confirms the increase of the sulphuric moiety: with the histochemical techniques of tannin-hiron chloride and lanthanum nitrate as ultrastructural tracers we can better attribute this result to proteic or glycoproteic substrata. In the uveal melanoma, in fact, the microanalytic result seems to be independent of the amount of pigment but is rather related to the proteic structure of the...
The X-ray microanalysis technique applied to a conventional transmission electron microscope is presented. This is a new way for the pathologist to recognize the composition (= the elements) of a definite area in the specimen. This technique originates from the X-ray fluorescence principle and gives us a qualitative and semi-quantitative analysis: with the simultaneous application of ultrastructural tracers we gain some information on many subjects of ultrastructural pathology.
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