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Characterizations are obtained for those pairs of weight functions u and v for which the operators $Tf\left(x\right)={ʃ}_{a\left(x\right)}^{b\left(x\right)}f\left(t\right)dt$ with a and b certain non-negative functions are bounded from $L_u^p(0,\infty )$ to $L_v^q(0,\infty )$, 0 < p,q < ∞, p≥ 1. Sufficient conditions are given for T to be bounded on the cones of monotone functions. The results are applied to give a weighted inequality comparing differences and derivatives as well as a weight characterization for the Steklov operator.