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We present a brief review of molecular biological basis and mathematical modelling of circadian rhythms in . We discuss pertinent aspects of a new model
that incorporates the transcriptional feedback loops revealed so far in the network of the
circadian clock (PER/TIM and VRI/PDP1 loops). Conventional Hill functions are not used
to describe the regulation of genes, instead the explicit reactions of binding and unbinding
processes of transcription factors to promoters are probabilistically modelled....
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