Gradient method for finding optimal scheduling in infinite dimensional models of chemotherapy.
Smieja, Jaroslaw, Swierniak, Andrzej, Duda, Zdzislaw (2000)
Journal of Theoretical Medicine
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Displaying similar documents to “Optimal control of combined therapy in a single strain HIV-1 model.”
Gradient method for finding optimal scheduling in infinite dimensional models of chemotherapy.
A mathematical model describing cellular division with a proliferating phase duration depending on the maturity of cells.
Adimy, Mostafa, Pujo-Menjouet, Laurent (2003)
Electronic Journal of Differential Equations (EJDE) [electronic only]
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Seeking bang-bang solutions of mixed immuno-chemotherapy of tumors.
Pillis, Lisette G.de, Fister, K.Renee, Gu, Weiqing, Collins, Craig, Daub, Michael, Gross, David, Moore, James, Preskill, Ben (2007)
Electronic Journal of Differential Equations (EJDE) [electronic only]
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A mathematical tumor model with immune resistance and drug therapy: An optimal control approach.
de Pillis, L.G., Radunskaya, A. (2001)
Journal of Theoretical Medicine
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Delay Dynamics of Cancer and Immune Cell Model
D. Adongo, K.R. Fister (2012)
Mathematical Modelling of Natural Phenomena
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We investigate optimal control of a cancer-immune cell interactive model with delay in the interphase compartment. By applying the optimal control theory, we seek to minimize the cost associated with the chemotherapy drug, minimize the accumulation of cancer cells, and increase the immune cell presence. Optimality conditions and characterization of the control are provided. Numerical analyses are given to enhance the understanding of the ...