Displaying similar documents to “A Class of Non Binary Unequally Replicated E-Optimal Designs.”

Some D-optimal chemical balance weighing designs: theory and examples

Bronisław Ceranka, Małgorzata Graczyk (2017)

Biometrical Letters

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In this paper we study a certain kind of experimental designs called chemical balance weighing designs. We consider issues with regard to determining optimality conditions. We give new classes of designs in which we are able to determine an optimal design. Moreover, examples are given for the presented cases.

Adaptive biased-coin designs for clinical trials with several treatments

Anthony C. Atkinson (2004)

Discussiones Mathematicae Probability and Statistics

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Adaptive designs are used in phase III clinical trials for skewing the allocation pattern towards the better treatments. We use optimum design theory to provide a skewed biased-coin procedure for sequential designs with continuous responses. The skewed designs are used to provide adaptive designs, the performance of which is studied numerically for designs with three treatments. Important properties are loss and the proportion of allocation to inferior treatments. Regularisation to provide...