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Displaying similar documents to “Optimisation of time-scheduled regimen for anti-cancer drug infusion”

Widespread Immunity to Breast and Prostate Cancers is Predicted by a Novel Model that also Determines Sporadic and Hereditary Susceptible Population Sizes

I. Kramer (2010)

Mathematical Modelling of Natural Phenomena

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Natural immunity to breast and prostate cancers is predicted by a novel, saturated ordered mutation model fitted to USA (SEER) incidence data, a prediction consistent with the latest ideas in immunosurveillance. For example, the prevalence of natural immunity to breast cancer in the white female risk population is predicted to be 76.5%; this immunity may be genetic and, therefore, inherited. The modeling also predicts that 6.9% of White ...

Analysis of a Mathematical Model for the Molecular Mechanism of Fate Decision in Mammary Stem Cells

O. U. Kirnasovsky, Y. Kogan, Z. Agur (2008)

Mathematical Modelling of Natural Phenomena

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Recently, adult stem cells have become a focus of intensive biomedical research, but the complex regulation that allows a small population of stem cells to replenish depleted tissues is still unknown. It has been suggested that specific tissue structures delimit the spaces where stem cells undergo unlimited proliferation (). In contrast, mathematical analysis suggests that a feedback control of stem cells on their own proliferation and differentiation (denoted ) suffices for preserving...