Multidrug resistance and its reversal: Mathematical models.
Michelson, Seth (1997)
Journal of Theoretical Medicine
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Displaying similar documents to “ATP Production and Necrosis Formation in a Tumour Spheroid Model”
Multidrug resistance and its reversal: Mathematical models.
Multiscale modeling and mathematical problems related to tumor evolution and medical therapy.
Bellomo, Nicola, De Angelis, Elena, Preziosi, Luigi (2003)
Journal of Theoretical Medicine
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Spatial tumor-immune modeling.
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Individual Cell-Based Model for In-Vitro Mesothelial Invasion of Ovarian Cancer
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Mathematical Modelling of Natural Phenomena
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In vitro transmesothelial migration assays of ovarian cancer cells, isolated or aggregated in multicellular spheroids, are reproduced deducing suitable Cellular Potts Models (CPM). We show that the simulations are in good agreement with the experimental evidence and that the overall process is regulated by the activity of matrix metalloproteinases (MMPs) and by the interplay of the adhesive properties of the cells with the extracellular...