Displaying similar documents to “Analysis of a Mathematical Model for the Molecular Mechanism of Fate Decision in Mammary Stem Cells”

Quantitative Analysis of Melanocyte Migration Based on Automated Cell Tracking under Phase Contrast Microscopy Considering the Combined Influence of Cell Division and Cell-Matrix Interactions

V. Letort, S. Fouliard, G. Letort, I. Adanja, M. Kumasaka, S. Gallagher, O. Debeir, L. Larue, F. Xavier (2010)

Mathematical Modelling of Natural Phenomena

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The aim of this study was to describe and analyze the regulation and spatio-temporal dynamics of melanocyte migration and its coupling to cell division and interaction with the matrix. The melanocyte lineage is particularly interesting because it is involved in both embryonic development and oncogenesis/metastasis (melanoma). Biological experiments were performed on two melanocyte cell lines established from wild-type and -catenin-transgenic...

Modeling Morphogenesis and : Towards Quantitative, Predictive, Cell-based Modeling

R. M. H. Merks, P. Koolwijk (2009)

Mathematical Modelling of Natural Phenomena

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Cell-based, mathematical models help make sense of morphogenesis— cells organizing into shape and pattern—by capturing cell behavior in simple, purely descriptive models. Cell-based models then predict the tissue-level patterns the cells produce collectively. The first step in a cell-based modeling approach is to isolate sub-processes, the patterning capabilities of one or a few cell types in cell cultures. Cell-based models can then identify the mechanisms responsible for patterning...