Displaying similar documents to “Thymic presentation of autoantigens and the efficiency of negative selection.”

Regulation of p53 by siRNA in radiation treated cells: Simulation studies

Krzysztof Puszyński, Roman Jaksik, Andrzej Świerniak (2012)

International Journal of Applied Mathematics and Computer Science

Similarity:

Ionizing radiation activates a large variety of intracellular mechanisms responsible for maintaining appropriate cell functionality or activation of apoptosis which eliminates damaged cells from the population. The mechanism of such induced cellular death is widely used in radiotherapy in order to eliminate cancer cells, although in some cases it is highly limited by increased cellular radio-resistance due to aberrations in molecular regulation mechanisms of malignant cells. Despite...

Mathematical modeling of the competition between acquired immunity and cancer

Mikhail Kolev (2003)

International Journal of Applied Mathematics and Computer Science

Similarity:

In this paper we propose and analyse a model of the competition between cancer and the acquired immune system. The model is a system of integro-differential bilinear equations. The role of the humoral response is analyzed. The simulations are related to the immunotherapy of tumors with antibodies.