Displaying similar documents to “A haplotype block model for fine mapping of quantitative trait loci regulating HIV-1 pathogenesis.”

Theoretical Hyperbolic Model of a Partial Agonism: Explicit Formulas for Affinity, Efficacy and Amplification

Milanov, Peter, Pencheva, Nevena (2011)

Serdica Journal of Computing

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The quantitative analysis of receptor-mediated effect is based on experimental concentration-response data in which the independent variable, the concentration of a receptor ligand, is linked with a dependent variable, the biological response. The steps between the drug–receptor interaction and the subsequent biological effect are to some extent unknown. The shape of the fitting curve of the experimental data may give some in-sights into the nature of the concentration–receptor–response...