Displaying similar documents to “Bifurcating solutions to the monodomain model equipped with FitzHugh-Nagumo kinetics.”

Bifurcations in a modulation equation for alternans in a cardiac fiber

Shu Dai, David G. Schaeffer (2010)

ESAIM: Mathematical Modelling and Numerical Analysis

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While alternans in a single cardiac cell appears through a simple period-doubling bifurcation, in extended tissue the exact nature of the bifurcation is unclear. In particular, the phase of alternans can exhibit wave-like spatial dependence, either stationary or travelling, which is known as alternans. We study these phenomena in simple cardiac models through a modulation equation proposed by Echebarria-Karma. As shown in our previous paper, the zero solution of their equation may...

On a Model of Leukemia Development with a Spatial Cell Distribution

A. Ducrot, V. Volpert (2010)

Mathematical Modelling of Natural Phenomena

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In this paper we propose a mathematical model to describe the evolution of leukemia in the bone marrow. The model is based on a reaction-diffusion system of equations in a porous medium. We show the existence of two stationary solutions, one of them corresponds to the normal case and another one to the pathological case. The leukemic state appears as a result of a bifurcation when the normal state loses its stability. The critical conditions of leukemia development are determined by...

Waves of Autocrine Signaling in Patterned Epithelia

C. B. Muratov, S. Y. Shvartsman (2010)

Mathematical Modelling of Natural Phenomena

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A biophysical model describing long-range cell-to-cell communication by a diffusible signal mediated by autocrine loops in developing epithelia in the presence of a morphogenetic pre-pattern is introduced. Under a number of approximations, the model reduces to a particular kind of bistable reaction-diffusion equation with strong heterogeneity. In the case of the heterogeneity in the form of a long strip a detailed analysis of signal propagation...