Displaying similar documents to “Mathematical modelling of molecule evolution in protocells”

Coupled analytical and numerical approach to uncovering new regulatory mechanisms of intracellular processes

Jarosław Śmieja (2010)

International Journal of Applied Mathematics and Computer Science

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The paper deals with the analysis of signaling pathways aimed at uncovering new regulatory processes regulating cell responses. First, general issues of comparing simulation and experimental data are discussed, and various aspects of data normalization are covered. Then, a model of a particular signaling pathway, induced by Interferon-β, is briefly introduced. It serves as an example illustrating how mathematical modeling can be used for inferring the structure of a regulatory system...

A biochemical multi-species quality model of a drinking water distribution system for simulation and design

Krzysztof Arminski, Tomasz Zubowicz, Mietek A. Brdys (2013)

International Journal of Applied Mathematics and Computer Science

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Drinking Water Distribution Systems (DWDSs) play a key role in sustainable development of modern society. They are classified as critical infrastructure systems. This imposes a large set of highly demanding requirements on the DWDS operation and requires dedicated algorithms for on-line monitoring and control to tackle related problems. Requirements on DWDS availability restrict the usability of the real plant in the design phase. Thus, a proper model is crucial. Within this paper a...

Model based analysis of signaling pathways

Jarosław Smieja (2008)

International Journal of Applied Mathematics and Computer Science

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The paper is concerned with application of mathematical modeling to the analysis of signaling pathways. Two issues, deterministic modeling of gene transcription and model-driven discovery of regulatory elements, are dealt with. First, the biological background is given and the importance of the stochastic nature of biological processes is addressed. The assumptions underlying deterministic modeling are presented. Special emphasis is put on describing gene transcription. A framework for...