Displaying similar documents to “Relationship between the selection pressure and the rate of mutation accumulation”

Drift, draft and structure: some mathematical models of evolution

Alison M. Etheridge (2008)

Banach Center Publications

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Understanding the evolution of individuals which live in a structured and fluctuating environment is of central importance in mathematical population genetics. Here we outline some of the mathematical challenges arising from modelling structured populations, primarily focussing on the interplay between forwards in time models for the evolution of the population and backwards in time models for the genealogical trees relating individuals in a sample from that population. In addition to...

An age-dependent model describing the spread of panleucopenia virus within feline populations

W. E. Fitzgibbon, M. Langlais, J. J. Morgan, D. Pontier, C. Wolf (2003)

Banach Center Publications

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Global existence results and long time behavior are provided for a mathematical model describing the propagation of Feline Panleucopenia Virus (FPLV) within a domestic cat population; two transmission modes are involved: a direct one from infective cats to susceptible ones, and an indirect one from the contaminated environment to susceptible cats. A more severe impact of the virus on young cats requires an age-structured model.

Epidemiological Models With Parametric Heterogeneity : Deterministic Theory for Closed Populations

A.S. Novozhilov (2012)

Mathematical Modelling of Natural Phenomena

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We present a unified mathematical approach to epidemiological models with parametric heterogeneity, i.e., to the models that describe individuals in the population as having specific parameter (trait) values that vary from one individuals to another. This is a natural framework to model, e.g., heterogeneity in susceptibility or infectivity of individuals. We review, along with the necessary theory, the results obtained using the discussed...

Mathematical Modeling and Quantitative Analysis of the Demographic and Ecological Aspects of Russian Supermortality

A. K. Cherkashin, Ya. A. Leshchenko (2011)

Mathematical Modelling of Natural Phenomena

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We have carried out a polysystem analysis of the population dynamics by using a variety of hypotheses and their respective models based on different system interpretations of the phenomenon under investigation. Each of the models supplements standard dynamic equations for explaining the effects observed. A qualitative model-based analysis is made of the age-specific male mortality for a Siberian industrial city. The study revealed the ...

Ancestral processes with selection: Branching and Moran models

Ellen Baake, Robert Bialowons (2008)

Banach Center Publications

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We consider two versions of stochastic population models with mutation and selection. The first approach relies on a multitype branching process; here, individuals reproduce and change type (i.e., mutate) independently of each other, without restriction on population size. We analyse the equilibrium behaviour of this model, both in the forward and in the backward direction of time; the backward point of view emerges if the ancestry of individuals chosen randomly from the present population...

Generalization of the Kermack-McKendrick SIR Model to a Patchy Environment for a Disease with Latency

J. Li, X. Zou (2009)

Mathematical Modelling of Natural Phenomena

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In this paper, with the assumptions that an infectious disease has a fixed latent period in a population and the latent individuals of the population may disperse, we reformulate an SIR model for the population living in two patches (cities, towns, or countries etc.), which is a generalization of the classic Kermack-McKendrick SIR model. The model is given by a system of delay differential equations with a fixed delay accounting for the latency and non-local terms caused by the mobility...

Do Demographic and Disease Structures Affect the Recurrence of Epidemics ?

A. Castellazzo, A. Mauro, C. Volpe, E. Venturino (2012)

Mathematical Modelling of Natural Phenomena

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In this paper we present an epidemic model affecting an age-structured population. We show by numerical simulations that this demographic structure can induce persistent oscillations in the epidemic. The model is then extended to encompass a stage-structured disease within an age-dependent population. In this case as well, persistent oscillations are observed in the infected as well as in the whole population.

Linking population genetics to phylogenetics

Paul G. Higgs (2008)

Banach Center Publications

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Population geneticists study the variability of gene sequences within a species, whereas phylogeneticists compare gene sequences between species and usually have only one representative sequence per species. Stochastic models in population genetics are used to determine probability distributions for gene frequencies and to predict the probability that a new mutation will become fixed in a population. Stochastic models in phylogenetics describe the substitution process in the single sequence...