On the discrete kinetic theory for active particles. Modelling the immune competition.
Brazzoli, I., Chauviere, A. (2006)
Computational & Mathematical Methods in Medicine
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Brazzoli, I., Chauviere, A. (2006)
Computational & Mathematical Methods in Medicine
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Mikhail Kolev (2003)
International Journal of Applied Mathematics and Computer Science
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In this paper we propose and analyse a model of the competition between cancer and the acquired immune system. The model is a system of integro-differential bilinear equations. The role of the humoral response is analyzed. The simulations are related to the immunotherapy of tumors with antibodies.
Arlotti, Luisa, Gamba, Andrea, Lachowicz, Miroslaw (2002)
Journal of Theoretical Medicine
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Bellomo, Nicola, De Angelis, Elena, Preziosi, Luigi (2003)
Journal of Theoretical Medicine
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Ambrosi, D., Bellomo, N., Preziosi, L. (2002)
Journal of Theoretical Medicine
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N. Bessonov, P. Kurbatova, V. Volpert (2010)
Mathematical Modelling of Natural Phenomena
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Evolution of cell populations can be described with dissipative particle dynamics, where each cell moves according to the balance of forces acting on it, or with partial differential equations, where cell population is considered as a continuous medium. We compare these two approaches for some model examples
de Pillis, L.G., Mallet, D.G., Radunskaya, A.E. (2006)
Computational & Mathematical Methods in Medicine
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K. M. Page (2009)
Mathematical Modelling of Natural Phenomena
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Many tumours undergo periods in which they apparently do not grow but remain at a roughly constant size for extended periods. This is termed tumour dormancy. The mechanisms responsible for dormancy include failure to develop an internal blood supply, individual tumour cells exiting the cell cycle and a balance between the tumour and the immune response to it. Tumour dormancy is of considerable importance in the natural history of cancer. In many cancers, and in particular in breast cancer,...
S. N. Gentry, R. Ashkenazi, T. L. Jackson (2009)
Mathematical Modelling of Natural Phenomena
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Most mammalian tissues are organized into a hierarchical structure of stem, progenitor, and differentiated cells. Tumors exhibit similar hierarchy, even if it is abnormal in comparison with healthy tissue. In particular, it is believed that a small population of cancer stem cells drives tumorigenesis in certain malignancies. These cancer stem cells are derived from transformed stem cells or mutated progenitors that have acquired stem-cell qualities, specifically the ability to self-renew....