Displaying similar documents to “Indirect inference for survival data.”

Survival analysis with coarsely observed covariates.

Soren Feodor Nielsen (2003)

SORT

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In this paper we consider analysis of survival data with incomplete covariate information. We model the incomplete covariates as a random coarsening of the complete covariate, and an overview of the theory of coarsening at random is given. Various ways of estimating the parameters of the model for the survival data given the covariates are discussed and compared.

Study of Bootstrap Estimates in Cox Regression Model with Delayed Entry

Silvie Bělašková, Eva Fišerová, Sylvia Krupičková (2013)

Acta Universitatis Palackianae Olomucensis. Facultas Rerum Naturalium. Mathematica

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In most clinical studies, patients are observed for extended time periods to evaluate influences in treatment such as drug treatment, approaches to surgery, etc. The primary event in these studies is death, relapse, adverse drug reaction, or development of a new disease. The follow-up time may range from few weeks to many years. Although these studies are long term, the number of observed events is small. Longitudinal studies have increased the importance of statistical methods for time-to...

A comparison of parametric models for mortality graduation. Application to mortality data for the Valencia Region (Spain).

Ana Debón, Francisco Montes, Ramón Sala (2005)

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The parametric graduation of mortality data has as its objective the satisfactory estimation of the death rates based on mortality data but using an age-dependent function whose parameters are adjusted from the crude rates obtainable directly from the data. This paper proposes a revision of the most commonly used parametric models and compares the result obtained with each of them when they are applied to the mortality data for the Valencia Region. As a result of the comparison, we conclude...

A sensitivity analysis for causal parameters in structural proportional hazards models.

Els Goetghebeur, Tom Loeys (2003)

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Deviations from assigned treatment occur often in clinical trials. In such a setting, the traditional intent-to-treat analysis does not measure biological efficacy but rather programmatic effectiveness. For all-or-nothing compliance situation, Loeys and Goetghebeur (2003) recently proposed a Structural Proportional Hazards method. It allows for casual estimation in the complier subpopulation provided the exclusion restriction holds: randomization per se has no effect unless exposure...

Likelihood for random-effect models (with discussion).

Youngjo Lee, John A. Nelder (2005)

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For inferences from random-effect models Lee and Nelder (1996) proposed to use hierarchical likelihood (h-likelihood). It allows influence from models that may include both fixed and random parameters. Because of the presence of unobserved random variables h-likelihood is not a likelihood in the Fisherian sense. The Fisher likelihood framework has advantages such as generality of application, statistical and computational efficiency. We introduce an extended likelihood framework and...