Modeling Pulsatility in the Human Cardiovascular System

de los Reyes V, Aurelio; Kappel, Franz

Mathematica Balkanica New Series (2010)

  • Volume: 24, Issue: 3-4, page 229-242
  • ISSN: 0205-3217

Abstract

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AMS Subj. Classification: 92C30In this study we investigated, modified and combined two existing mathematical cardiovascular models, a non-pulsatile global model and a simplified pulsatile left heart model. The first goal of the study was to integrate these models. The main objective is to have a global lumped parameter pulsatile model that predicts the pressures in the systemic and pulmonary circulation, and specifically the pulsatile pressures in the the finger arteries where real-time measurements can be obtained. Modifications were made in the ventricular elastance to model the stiffness of heart muscles under stress or exercise state. The systemic aorta compartment is added to the combined model. A finger artery compartment is included to reflect measurements of pulsatile pressures. Parameters were estimated to simulate an average normal blood pressures. Preliminary simulation results are presented.

How to cite

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de los Reyes V, Aurelio, and Kappel, Franz. "Modeling Pulsatility in the Human Cardiovascular System." Mathematica Balkanica New Series 24.3-4 (2010): 229-242. <http://eudml.org/doc/11344>.

@article{delosReyesV2010,
abstract = {AMS Subj. Classification: 92C30In this study we investigated, modified and combined two existing mathematical cardiovascular models, a non-pulsatile global model and a simplified pulsatile left heart model. The first goal of the study was to integrate these models. The main objective is to have a global lumped parameter pulsatile model that predicts the pressures in the systemic and pulmonary circulation, and specifically the pulsatile pressures in the the finger arteries where real-time measurements can be obtained. Modifications were made in the ventricular elastance to model the stiffness of heart muscles under stress or exercise state. The systemic aorta compartment is added to the combined model. A finger artery compartment is included to reflect measurements of pulsatile pressures. Parameters were estimated to simulate an average normal blood pressures. Preliminary simulation results are presented.},
author = {de los Reyes V, Aurelio, Kappel, Franz},
journal = {Mathematica Balkanica New Series},
keywords = {Mathematical Cardiovascular Model; Pulsatility; Contractility; Left Ventricular Elastance; mathematical cardiovascular model; pulsatility; contractility; left ventricular elastance},
language = {eng},
number = {3-4},
pages = {229-242},
publisher = {Bulgarian Academy of Sciences - National Committee for Mathematics},
title = {Modeling Pulsatility in the Human Cardiovascular System},
url = {http://eudml.org/doc/11344},
volume = {24},
year = {2010},
}

TY - JOUR
AU - de los Reyes V, Aurelio
AU - Kappel, Franz
TI - Modeling Pulsatility in the Human Cardiovascular System
JO - Mathematica Balkanica New Series
PY - 2010
PB - Bulgarian Academy of Sciences - National Committee for Mathematics
VL - 24
IS - 3-4
SP - 229
EP - 242
AB - AMS Subj. Classification: 92C30In this study we investigated, modified and combined two existing mathematical cardiovascular models, a non-pulsatile global model and a simplified pulsatile left heart model. The first goal of the study was to integrate these models. The main objective is to have a global lumped parameter pulsatile model that predicts the pressures in the systemic and pulmonary circulation, and specifically the pulsatile pressures in the the finger arteries where real-time measurements can be obtained. Modifications were made in the ventricular elastance to model the stiffness of heart muscles under stress or exercise state. The systemic aorta compartment is added to the combined model. A finger artery compartment is included to reflect measurements of pulsatile pressures. Parameters were estimated to simulate an average normal blood pressures. Preliminary simulation results are presented.
LA - eng
KW - Mathematical Cardiovascular Model; Pulsatility; Contractility; Left Ventricular Elastance; mathematical cardiovascular model; pulsatility; contractility; left ventricular elastance
UR - http://eudml.org/doc/11344
ER -

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