Modélisation longitudinale de données incomplètes : exemple de la charge virale plasmatique du VIH

Rodolphe Thiébaut; Hélène Jacqmin-Gadda

Journal de la société française de statistique (2004)

  • Volume: 145, Issue: 2, page 33-47
  • ISSN: 1962-5197

How to cite


Thiébaut, Rodolphe, and Jacqmin-Gadda, Hélène. "Modélisation longitudinale de données incomplètes : exemple de la charge virale plasmatique du VIH." Journal de la société française de statistique 145.2 (2004): 33-47. <>.

author = {Thiébaut, Rodolphe, Jacqmin-Gadda, Hélène},
journal = {Journal de la société française de statistique},
language = {fre},
number = {2},
pages = {33-47},
publisher = {Société française de statistique},
title = {Modélisation longitudinale de données incomplètes : exemple de la charge virale plasmatique du VIH},
url = {},
volume = {145},
year = {2004},

AU - Thiébaut, Rodolphe
AU - Jacqmin-Gadda, Hélène
TI - Modélisation longitudinale de données incomplètes : exemple de la charge virale plasmatique du VIH
JO - Journal de la société française de statistique
PY - 2004
PB - Société française de statistique
VL - 145
IS - 2
SP - 33
EP - 47
LA - fre
UR -
ER -


  1. ALBERT J. M., IOANNIDIS J. P. A., REICHELDERFER P., CONWAY B., COOMBS R. W., CRANE L., DEMASI R., DIXON D. O., FLANDRE P., HUGHES M. D., KALISH L. A., LARNTZ K., LIN D. Y., MARSCHNER I. C., MUNOZ A., MURRAY J., NEATON J., PETTINELLI C. , RIDA W., TAYLOR J. M. G. and WELLES S. L. (1998). Statistical issues for HIV surrogate endpoints : Point/counterpoint. Statistics in Medicine, 17, 2435-62. 
  2. BERK K. N. and LACHENBRUCH P. A. (2002). Repeated measures with zeros. Statistical Methods in Medical Research, 11, 303-16. Zbl1121.62574
  3. DE GRUTTOLA V. and Tu X. M. (1994). Modelling progression of CD4-lymphocyte count and its relationship to survival time. Biometrics, 50, 1003-14. Zbl0825.62792
  4. DELFRAISSY J. F. (2002). Prise en charge des personnes infectées par le VIH. Recommandations du groupe d'experts. Paris, Médecine-Sciences Flammarion. 
  5. GUO X. and CARLIN P. (2004). Separate and joint modelling of longitudinal and event time data using standard computer packages. The American Statistician, 58, 1-9. MR2055507
  6. HENDERSON R., DIGGLE P. and DOBSON A. (2000). Joint modelling of longitudinal measurements and event time data. Biostatistics, 1, 465-80. Zbl1089.62519
  7. HUGHES J. P. (1999). Mixed effects models with censored data with application to HIV RNA levels. Biometrics, 55, 625-9. Zbl1059.62661
  8. JACQMIN-GADDA H. and THIÉBAUT R. (2004). Modèles de sélection pour données longitudinales gaussiennes : Application à l'étude du vieillissement cognitif. Journal de la Société Française de Statistique, (sous presse). 
  9. JACQMIN-GADDA H., THIÉBAUT R., CHÊNE G. and COMMENGES D. (2000). Analysis of left-censored longitudinal data with application to viral load in HIV infection. Biostatistics, 1, 355-68. Zbl1096.62507
  10. KENWARD M. G. (1998). Selection models for repeated measurements with non-random dropout : an illustration of sensitivity. Statistics in Medicine, 17, 2723-32. 
  11. LAIRD N. M. and WARE J. H. (1982). Random-effects models for longitudinal data. Biometrics, 38, 963-74. Zbl0512.62107
  12. LITTELL R. C. , MILLIKEN G. A., STROUP W. W. and WOLFINGER R. D. (1996). SAS System for Mixed Models. Cary, NC, SAS Institute. 
  13. LITTLE R. (1995). Modeling the drop-out mechanism in repeated-measures studies. Journal of the American Statistical Association, 90, 1112-21. Zbl0841.62099MR1354029
  14. LYLES R. H., LYLES C. M. and TAYLOR D. J. (2000). Random regression models for human immunodeficiency virus ribonucleic acid data subject to left censoring and informative drop-outs. Journal of the Royal Statistical Society : Series C, 49, 485-97. Zbl0965.62097MR1824554
  15. MELLORS J. W., MUOZ A., GIORGI J. V., MARGOLICK J. B., TASSONI C. J., GUPTA P., KINGSLEY L. A., TODD J. A., SAAH A. J., DETELS R., PHAIR J. P. and RINALDO C. R., Jr. (1997). Plasma viral load and CD4+ lymphocytes as prognostic markers of HIV-1 infection. Annals of Internal Medicine, 126, 946-54. 
  16. MININI P. and CHAVANCE M. (2004). Observations longitudinales incomplètes : de la modélisation des observations disponibles à l'analyse de sensibilité. Journal de la Société Française de Statistique, 145, 2, 5-18. 
  17. MOULTON L. H. and HALSEY N. A. (1995). A mixture model with detection limits for regression analyses of antibody response to vaccine. Biometrics, 51 , 1570-8. Zbl0875.62502
  18. PINHEIRO J. C. and BATES D. M. (2000). Mixed-Effects Models in S and S-PLUS. New York, Springer-Verlag. Zbl0953.62065
  19. RUBIN D. (1976). Inference and missing data. Biometrika, 63, 581-92. Zbl0344.62034MR455196
  20. THIÉBAUT R., CHÊNE G., JACQMIN-GADDA H., MORLAT P., MERCIÉ P., DUPON M., NEAU D., RAMAROSON H., DABIS F. and SALAMON R. (2003). Time updated CD4+ T Lymphocyte count and HIV RNA as major markers of disease progression in naive HIV-1 infected patients treated with an highly active antiretroviral therapy. The Aquitaine Cohort, 1996-2001. Journal of Acquired Immune Deficiency Syndromes, 33, 380-6. 
  21. THIÉBAUT R. and JACQMIN-GADDA H. (2004). Mixed models for longitudinal left-censored repeated measures. Computer Methods and Programs in Biomedicine, 74, 255-60. 
  22. VERBEKE G. and MOLENBERGHS G. (2000). Linear mixed models for longitudinal data. New York, Springer. Zbl0956.62055MR1880596

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