Mathematical model of tumour cord growth along the source of nutrient

S. Astanin; A. Tosin

Mathematical Modelling of Natural Phenomena (2010)

  • Volume: 2, Issue: 3, page 153-177
  • ISSN: 0973-5348

Abstract

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A mathematical model of the tumour growth along a blood vessel is proposed. The model employs the mixture theory approach to describe a tissue which consists of cells, extracellular matrix and liquid. The growing tumour tissue is supposed to be surrounded by the host tissue. Tumours where complete oxydation of glucose prevails are considered. Special attention is paid to consistent description of oxygen consumption and growth processes based on the energy balance. A finite difference numerical method is proposed. The level set method is used to track an interface between the tissues. The simulations show localization of the tumour within a limited distance from the vessels and constant expansion velocity along the vessels.

How to cite

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Astanin, S., and Tosin, A.. "Mathematical model of tumour cord growth along the source of nutrient." Mathematical Modelling of Natural Phenomena 2.3 (2010): 153-177. <http://eudml.org/doc/222323>.

@article{Astanin2010,
abstract = { A mathematical model of the tumour growth along a blood vessel is proposed. The model employs the mixture theory approach to describe a tissue which consists of cells, extracellular matrix and liquid. The growing tumour tissue is supposed to be surrounded by the host tissue. Tumours where complete oxydation of glucose prevails are considered. Special attention is paid to consistent description of oxygen consumption and growth processes based on the energy balance. A finite difference numerical method is proposed. The level set method is used to track an interface between the tissues. The simulations show localization of the tumour within a limited distance from the vessels and constant expansion velocity along the vessels.},
author = {Astanin, S., Tosin, A.},
journal = {Mathematical Modelling of Natural Phenomena},
keywords = {tumour growth; hypoxia; tumour cords; tumour-host interface; mathematical model; mixture theory; finite difference; level set method; mixture theory},
language = {eng},
month = {3},
number = {3},
pages = {153-177},
publisher = {EDP Sciences},
title = {Mathematical model of tumour cord growth along the source of nutrient},
url = {http://eudml.org/doc/222323},
volume = {2},
year = {2010},
}

TY - JOUR
AU - Astanin, S.
AU - Tosin, A.
TI - Mathematical model of tumour cord growth along the source of nutrient
JO - Mathematical Modelling of Natural Phenomena
DA - 2010/3//
PB - EDP Sciences
VL - 2
IS - 3
SP - 153
EP - 177
AB - A mathematical model of the tumour growth along a blood vessel is proposed. The model employs the mixture theory approach to describe a tissue which consists of cells, extracellular matrix and liquid. The growing tumour tissue is supposed to be surrounded by the host tissue. Tumours where complete oxydation of glucose prevails are considered. Special attention is paid to consistent description of oxygen consumption and growth processes based on the energy balance. A finite difference numerical method is proposed. The level set method is used to track an interface between the tissues. The simulations show localization of the tumour within a limited distance from the vessels and constant expansion velocity along the vessels.
LA - eng
KW - tumour growth; hypoxia; tumour cords; tumour-host interface; mathematical model; mixture theory; finite difference; level set method; mixture theory
UR - http://eudml.org/doc/222323
ER -

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