Self-Assembly of Icosahedral Viral Capsids: the Combinatorial Analysis Approach
Mathematical Modelling of Natural Phenomena (2011)
- Volume: 6, Issue: 6, page 136-158
- ISSN: 0973-5348
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topKerner, R.. "Self-Assembly of Icosahedral Viral Capsids: the Combinatorial Analysis Approach." Mathematical Modelling of Natural Phenomena 6.6 (2011): 136-158. <http://eudml.org/doc/222354>.
@article{Kerner2011,
abstract = {An analysis of all possible icosahedral viral capsids is proposed. It takes into account
the diversity of coat proteins and their positioning in elementary pentagonal and
hexagonal configurations, leading to definite capsid size. We show that the
self-organization of observed capsids during their production implies a definite
composition and configuration of elementary building blocks. The exact number of different
protein dimers is related to the size of a given capsid, labeled by its
T-number. Simple rules determining these numbers for each value of
T are deduced and certain consequences concerning the probabilities of
mutations and evolution of capsid viruses are discussed. },
author = {Kerner, R.},
journal = {Mathematical Modelling of Natural Phenomena},
keywords = {viral capsid growth; self-organized agglomeration; symmetry},
language = {eng},
month = {10},
number = {6},
pages = {136-158},
publisher = {EDP Sciences},
title = {Self-Assembly of Icosahedral Viral Capsids: the Combinatorial Analysis Approach},
url = {http://eudml.org/doc/222354},
volume = {6},
year = {2011},
}
TY - JOUR
AU - Kerner, R.
TI - Self-Assembly of Icosahedral Viral Capsids: the Combinatorial Analysis Approach
JO - Mathematical Modelling of Natural Phenomena
DA - 2011/10//
PB - EDP Sciences
VL - 6
IS - 6
SP - 136
EP - 158
AB - An analysis of all possible icosahedral viral capsids is proposed. It takes into account
the diversity of coat proteins and their positioning in elementary pentagonal and
hexagonal configurations, leading to definite capsid size. We show that the
self-organization of observed capsids during their production implies a definite
composition and configuration of elementary building blocks. The exact number of different
protein dimers is related to the size of a given capsid, labeled by its
T-number. Simple rules determining these numbers for each value of
T are deduced and certain consequences concerning the probabilities of
mutations and evolution of capsid viruses are discussed.
LA - eng
KW - viral capsid growth; self-organized agglomeration; symmetry
UR - http://eudml.org/doc/222354
ER -
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