Optimal placement of electrodes in an electroporation process

Nicolae Cîndea; Benoît Fabrèges; Frédéric de Gournay; Clair Poignard

ESAIM: Proceedings (2010)

  • Volume: 30, page 34-43
  • ISSN: 1270-900X

Abstract

top
Electroporation consists in increasing the permeability of a tissue by applying high voltage pulses. In this paper we discuss the question of optimal placement and optimal loading of electrodes such that electroporation holds only in a given open set of the domain. The electroporated set of the domain is where the norm of the electric field is above a given threshold value. We use a standard gradient algorithm to optimize the loading of the electrodes and shape sensitivity analysis and a gradient algorithm in order to move the electrodes. We also discuss the choice of objective functions to be chosen in the gradient algorithm.

How to cite

top

Cîndea, Nicolae, et al. Bresch, D., et al, eds. "Optimal placement of electrodes in an electroporation process." ESAIM: Proceedings 30 (2010): 34-43. <http://eudml.org/doc/251211>.

@article{Cîndea2010,
abstract = {Electroporation consists in increasing the permeability of a tissue by applying high voltage pulses. In this paper we discuss the question of optimal placement and optimal loading of electrodes such that electroporation holds only in a given open set of the domain. The electroporated set of the domain is where the norm of the electric field is above a given threshold value. We use a standard gradient algorithm to optimize the loading of the electrodes and shape sensitivity analysis and a gradient algorithm in order to move the electrodes. We also discuss the choice of objective functions to be chosen in the gradient algorithm.},
author = {Cîndea, Nicolae, Fabrèges, Benoît, de Gournay, Frédéric, Poignard, Clair},
editor = {Bresch, D., Calvez, V., Grenier, E., Vigneaux, P., Gerbeau, J-F.},
journal = {ESAIM: Proceedings},
keywords = {standard gradient algorithm; sensitivity analysis},
language = {eng},
month = {12},
pages = {34-43},
publisher = {EDP Sciences},
title = {Optimal placement of electrodes in an electroporation process},
url = {http://eudml.org/doc/251211},
volume = {30},
year = {2010},
}

TY - JOUR
AU - Cîndea, Nicolae
AU - Fabrèges, Benoît
AU - de Gournay, Frédéric
AU - Poignard, Clair
AU - Bresch, D.
AU - Calvez, V.
AU - Grenier, E.
AU - Vigneaux, P.
AU - Gerbeau, J-F.
TI - Optimal placement of electrodes in an electroporation process
JO - ESAIM: Proceedings
DA - 2010/12//
PB - EDP Sciences
VL - 30
SP - 34
EP - 43
AB - Electroporation consists in increasing the permeability of a tissue by applying high voltage pulses. In this paper we discuss the question of optimal placement and optimal loading of electrodes such that electroporation holds only in a given open set of the domain. The electroporated set of the domain is where the norm of the electric field is above a given threshold value. We use a standard gradient algorithm to optimize the loading of the electrodes and shape sensitivity analysis and a gradient algorithm in order to move the electrodes. We also discuss the choice of objective functions to be chosen in the gradient algorithm.
LA - eng
KW - standard gradient algorithm; sensitivity analysis
UR - http://eudml.org/doc/251211
ER -

NotesEmbed ?

top

You must be logged in to post comments.