# Optimal placement of electrodes in an electroporation process

Nicolae Cîndea; Benoît Fabrèges; Frédéric de Gournay; Clair Poignard

ESAIM: Proceedings (2010)

- Volume: 30, page 34-43
- ISSN: 1270-900X

## Access Full Article

top## Abstract

top## How to cite

topCîndea, Nicolae, et al. Bresch, D., et al, eds. "Optimal placement of electrodes in an electroporation process." ESAIM: Proceedings 30 (2010): 34-43. <http://eudml.org/doc/251211>.

@article{Cîndea2010,

abstract = {Electroporation consists in increasing the permeability of a tissue by applying high
voltage pulses. In this paper we discuss the question of optimal placement and optimal
loading of electrodes such that electroporation holds only in a given open set of the
domain. The electroporated set of the domain is where the norm of the electric field is
above a given threshold value. We use a standard gradient algorithm to optimize the
loading of the electrodes and shape sensitivity analysis and a gradient algorithm in order
to move the electrodes. We also discuss the choice of objective functions to be chosen in
the gradient algorithm.},

author = {Cîndea, Nicolae, Fabrèges, Benoît, de Gournay, Frédéric, Poignard, Clair},

editor = {Bresch, D., Calvez, V., Grenier, E., Vigneaux, P., Gerbeau, J-F.},

journal = {ESAIM: Proceedings},

keywords = {standard gradient algorithm; sensitivity analysis},

language = {eng},

month = {12},

pages = {34-43},

publisher = {EDP Sciences},

title = {Optimal placement of electrodes in an electroporation process},

url = {http://eudml.org/doc/251211},

volume = {30},

year = {2010},

}

TY - JOUR

AU - Cîndea, Nicolae

AU - Fabrèges, Benoît

AU - de Gournay, Frédéric

AU - Poignard, Clair

AU - Bresch, D.

AU - Calvez, V.

AU - Grenier, E.

AU - Vigneaux, P.

AU - Gerbeau, J-F.

TI - Optimal placement of electrodes in an electroporation process

JO - ESAIM: Proceedings

DA - 2010/12//

PB - EDP Sciences

VL - 30

SP - 34

EP - 43

AB - Electroporation consists in increasing the permeability of a tissue by applying high
voltage pulses. In this paper we discuss the question of optimal placement and optimal
loading of electrodes such that electroporation holds only in a given open set of the
domain. The electroporated set of the domain is where the norm of the electric field is
above a given threshold value. We use a standard gradient algorithm to optimize the
loading of the electrodes and shape sensitivity analysis and a gradient algorithm in order
to move the electrodes. We also discuss the choice of objective functions to be chosen in
the gradient algorithm.

LA - eng

KW - standard gradient algorithm; sensitivity analysis

UR - http://eudml.org/doc/251211

ER -

## NotesEmbed ?

topTo embed these notes on your page include the following JavaScript code on your page where you want the notes to appear.