Mucus dynamics subject to air and wall motion*

S. Enault; D. Lombardi; P. Poncet; M. Thiriet

ESAIM: Proceedings (2010)

  • Volume: 30, page 124-141
  • ISSN: 1270-900X

Abstract

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This study presents a numerical investigation of basic interactions between respiratory mucus motion, air circulation and epithelium ciliated cells vibration. One focuses on identification of meaningful rheological parameters, physiological and numerical simulation dimensioning. These preliminary results are crucial before the study of more general configurations of respiratory mucus motion. The numerical study presented in this work aims at providing a first numerical tool able to simulate the effects of mucus mobility and its ability to carry out pathogens or to deliver aerosol therapy to membrane wall cells. Momentum diffusion is identified as the dominant effect, as expected in this micrometer scale configuration, and its associate momentum diffusion operator is shown to be extremely stiff. Furthermore, epithelium vibration is shown to be much more efficient than air circulation for mucus propulsion.

How to cite

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Enault, S., et al. Bresch, D., et al, eds. " Mucus dynamics subject to air and wall motion*." ESAIM: Proceedings 30 (2010): 124-141. <http://eudml.org/doc/251221>.

@article{Enault2010,
abstract = {This study presents a numerical investigation of basic interactions between respiratory mucus motion, air circulation and epithelium ciliated cells vibration. One focuses on identification of meaningful rheological parameters, physiological and numerical simulation dimensioning. These preliminary results are crucial before the study of more general configurations of respiratory mucus motion. The numerical study presented in this work aims at providing a first numerical tool able to simulate the effects of mucus mobility and its ability to carry out pathogens or to deliver aerosol therapy to membrane wall cells. Momentum diffusion is identified as the dominant effect, as expected in this micrometer scale configuration, and its associate momentum diffusion operator is shown to be extremely stiff. Furthermore, epithelium vibration is shown to be much more efficient than air circulation for mucus propulsion.},
author = {Enault, S., Lombardi, D., Poncet, P., Thiriet, M.},
editor = {Bresch, D., Calvez, V., Grenier, E., Vigneaux, P., Gerbeau, J-F.},
journal = {ESAIM: Proceedings},
language = {eng},
month = {12},
pages = {124-141},
publisher = {EDP Sciences},
title = { Mucus dynamics subject to air and wall motion*},
url = {http://eudml.org/doc/251221},
volume = {30},
year = {2010},
}

TY - JOUR
AU - Enault, S.
AU - Lombardi, D.
AU - Poncet, P.
AU - Thiriet, M.
AU - Bresch, D.
AU - Calvez, V.
AU - Grenier, E.
AU - Vigneaux, P.
AU - Gerbeau, J-F.
TI - Mucus dynamics subject to air and wall motion*
JO - ESAIM: Proceedings
DA - 2010/12//
PB - EDP Sciences
VL - 30
SP - 124
EP - 141
AB - This study presents a numerical investigation of basic interactions between respiratory mucus motion, air circulation and epithelium ciliated cells vibration. One focuses on identification of meaningful rheological parameters, physiological and numerical simulation dimensioning. These preliminary results are crucial before the study of more general configurations of respiratory mucus motion. The numerical study presented in this work aims at providing a first numerical tool able to simulate the effects of mucus mobility and its ability to carry out pathogens or to deliver aerosol therapy to membrane wall cells. Momentum diffusion is identified as the dominant effect, as expected in this micrometer scale configuration, and its associate momentum diffusion operator is shown to be extremely stiff. Furthermore, epithelium vibration is shown to be much more efficient than air circulation for mucus propulsion.
LA - eng
UR - http://eudml.org/doc/251221
ER -

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