Thermodynamics of DNA microarrays

Enrico Carlon. "Thermodynamics of DNA microarrays." Banach Center Publications 80.1 (2008): 229-233. <http://eudml.org/doc/282491>.

@article{EnricoCarlon2008,
abstract = {DNA microarrays have been widely used in molecular biology laboratories. The main current application of these devices is the determination of the gene expression level for thousands of genes simultaneously. Here we review a recently introduced physical model for hybridization (i.e. the binding of complementary DNA strands) in Affymetrix arrays and compare it to experimental results. The experimental data follow rather well the microscopic model and the approach offers several advantages compared to traditional methods of microarray data analysis.},
author = {Enrico Carlon},
journal = {Banach Center Publications},
keywords = {DNA hybridization},
language = {eng},
number = {1},
pages = {229-233},
title = {Thermodynamics of DNA microarrays},
url = {http://eudml.org/doc/282491},
volume = {80},
year = {2008},
}

TY - JOUR
AU - Enrico Carlon
TI - Thermodynamics of DNA microarrays
JO - Banach Center Publications
PY - 2008
VL - 80
IS - 1
SP - 229
EP - 233
AB - DNA microarrays have been widely used in molecular biology laboratories. The main current application of these devices is the determination of the gene expression level for thousands of genes simultaneously. Here we review a recently introduced physical model for hybridization (i.e. the binding of complementary DNA strands) in Affymetrix arrays and compare it to experimental results. The experimental data follow rather well the microscopic model and the approach offers several advantages compared to traditional methods of microarray data analysis.
LA - eng
KW - DNA hybridization
UR - http://eudml.org/doc/282491
ER -