Sintesi di acidi ribonucleici e di proteine nelle diverse regioni dell'embrione di Xenopus laevis

Marisa Leonardi Cigada; Fiorenza Laria De Bernardi; Anna Maria Scarpetti Bolzern

Atti della Accademia Nazionale dei Lincei. Classe di Scienze Fisiche, Matematiche e Naturali. Rendiconti (1975)

  • Volume: 59, Issue: 1-2, page 152-163
  • ISSN: 0392-7881

Abstract

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An analysis of RNA and protein synthesis has been carried out on Xenopus laevis embryos, cut into two portions, during the early stages of their development. Actinomycin D was employed to inhibit the synthesis. The action of actinomycin on synthesis is stronger during gastrulation than during neurulation. In each stage a correlation between RNA synthesis inhibition and protein synthesis inhibition has been observed. In the ventral fragments of the neurula the ratio between the two inhibitions is 1:1, in the dorsal fragments it is 2:1. Messengers which existed before the treatment with actinomycin D are likely to work in protein synthesis in the dorsal fragment. This fact may be thought to be in connection with the greater hystological differentiation of the dorsal fragments. Experiments carried out on embryos in a more advanced stage of development (st. 22) and cut into three pieces confirmed this hypothesis. We observe that inhibition of incorporation in RNA compared with the inhibition in proteins increases in the order: ventral portion, dorsal portion, head. In this last portion the incorporation in protein is increased in treated embryos. This fact seems to indicate that actinomycin D inhibits the messengers controlling protein turnover.

How to cite

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Leonardi Cigada, Marisa, Laria De Bernardi, Fiorenza, and Scarpetti Bolzern, Anna Maria. "Sintesi di acidi ribonucleici e di proteine nelle diverse regioni dell'embrione di Xenopus laevis." Atti della Accademia Nazionale dei Lincei. Classe di Scienze Fisiche, Matematiche e Naturali. Rendiconti 59.1-2 (1975): 152-163. <http://eudml.org/doc/290829>.

@article{LeonardiCigada1975,
author = {Leonardi Cigada, Marisa, Laria De Bernardi, Fiorenza, Scarpetti Bolzern, Anna Maria},
journal = {Atti della Accademia Nazionale dei Lincei. Classe di Scienze Fisiche, Matematiche e Naturali. Rendiconti},
language = {ita},
month = {7},
number = {1-2},
pages = {152-163},
publisher = {Accademia Nazionale dei Lincei},
title = {Sintesi di acidi ribonucleici e di proteine nelle diverse regioni dell'embrione di Xenopus laevis},
url = {http://eudml.org/doc/290829},
volume = {59},
year = {1975},
}

TY - JOUR
AU - Leonardi Cigada, Marisa
AU - Laria De Bernardi, Fiorenza
AU - Scarpetti Bolzern, Anna Maria
TI - Sintesi di acidi ribonucleici e di proteine nelle diverse regioni dell'embrione di Xenopus laevis
JO - Atti della Accademia Nazionale dei Lincei. Classe di Scienze Fisiche, Matematiche e Naturali. Rendiconti
DA - 1975/7//
PB - Accademia Nazionale dei Lincei
VL - 59
IS - 1-2
SP - 152
EP - 163
LA - ita
UR - http://eudml.org/doc/290829
ER -

References

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