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Non-Euclidean geometry and differential equations

A. Popov — 1996

Banach Center Publications

In this paper a geometrical link between partial differential equations (PDE) and special coordinate nets on two-dimensional smooth manifolds with the a priori given curvature is suggested. The notion of G-class (the Gauss class) of differential equations admitting such an interpretation is introduced. The perspective of this approach is the possibility of applying the instruments and methods of non-Euclidean geometry to the investigation of differential equations. The equations generated by the...

A Computational Framework to Assess the Efficacy of Cytotoxic Molecules and Vascular Disrupting Agents against Solid Tumours

M. Pons-SalortB. van der SandenA. JuhemA. PopovA. Stéphanou — 2012

Mathematical Modelling of Natural Phenomena

A computational framework for testing the effects of cytotoxic molecules, specific to a given phase of the cell cycle, and vascular disrupting agents (VDAs) is presented. The model is based on a cellular automaton to describe tumour cell states transitions from proliferation to death. It is coupled with a model describing the tumour vasculature and its adaptation to the blood rheological constraints when alterations are induced by VDAs treatment....

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