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In this paper, we are concerned with the existence of one-signed solutions of four-point boundary value problems $$-u^{\text{'}\text{'}}+Mu=rg\left(t\right)f\left(u\right),u\left(0\right)=u\left(\epsilon \right),u\left(1\right)=u(1-\epsilon )$$ and $$u^{\text{'}\text{'}}+Mu=rg\left(t\right)f\left(u\right),u\left(0\right)=u\left(\epsilon \right),u\left(1\right)=u(1-\epsilon ),$$ where $\epsilon \in (0,1/2)$, $M\in (0,\infty )$ is a constant and $r>0$ is a parameter, $g\in C\left(\right[0,1],(0,+\infty \left)\right)$, $f\in C(ℝ,ℝ)$ with $sf\left(s\right)>0$ for $s\ne 0$. The proof of the main results is based upon bifurcation techniques.