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Stability analysis of nonlinear time-delayed systems with application to biological models

H.a. KruthikaArun D. MahindrakarRamkrishna Pasumarthy — 2017

International Journal of Applied Mathematics and Computer Science

In this paper, we analyse the local stability of a gene-regulatory network and immunotherapy for cancer modelled as nonlinear time-delay systems. A numerically generated kernel, using the sum-of-squares decomposition of multivariate polynomials, is used in the construction of an appropriate Lyapunov-Krasovskii functional for stability analysis of the networks around an equilibrium point. This analysis translates to verifying equivalent LMI conditions. A delay-independent asymptotic stability of...

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