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Let $V$ be a complex nonsingular projective 3-fold of general type. We prove $P_{12}\left(V\right):=dim{H}^0(V,12K_V)\>0$ and $P_{m_0}\left(V\right)\>1$ for some positive integer $m_0\le 24$. A direct consequence is the birationality of the pluricanonical map ${\varphi }_m$ for all $m\ge 126$. Besides, the canonical volume $\text{Vol}\left(V\right)$ has a universal lower bound $\nu \left(3\right)\ge \frac{1}{63·{126}^2}$.