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We discuss theoretical and experimental approaches to three distinct
developmental systems that illustrate how theory can influence experimental work
and . The chosen systems – ,
bacterial pattern formation, and pigmentation patterns – illustrate the
fundamental physical processes of signaling, growth and cell division, and cell
movement involved in pattern formation and development. These systems exemplify
the current state of theoretical and experimental understanding of how these
processes produce...
During vertebrate development cells acquire different fates depending largely on
their location in the embryo. The definition of a cell's developmental
fate relies on extensive intercellular communication that produces positional
information and ultimately generates an appropriately proportioned anatomy. Here
we place reaction-diffusion mechanisms in the context of general concepts
regarding the generation of positional information during development and then
focus on these mechanisms as parsimonious...
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