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The longitudinal regression model $Z_i^j=m({\theta }_0,{𝕏}_i\left(T_i^j\right))+{\epsilon }_i^j,$ where $Z_i^j$ is the $j$th measurement of the $i$th subject at random time $T_i^j$, $m$ is the regression function, ${𝕏}_i\left(T_i^j\right)$ is a predictable covariate process observed at time $T_i^j$ and ${\epsilon }_i^j$ is a noise, is studied in marked point process framework. In this paper we introduce the assumptions which guarantee the consistency and asymptotic normality of smooth $M$-estimator of unknown parameter ${\theta }_0$.