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Real-world medical decisions rarely involve binary Ðsole condition present or absent-
patterns of patient pathophysiology. Similarly, provider interventions are rarely unitary
in nature: the clinician often undertakes multiple interventions simultaneously.
Conventional approaches towards complex physiologic derangements and their associated
management focus on the frequencies of joint appearances, treating the individual
derangements of physiology...
Solid tumors and hematological cancers contain small population of tumor cells that are
believed to play a critical role in the development and progression of the disease. These
cells, named Cancer Stem Cells (CSCs), have been found in leukemia, myeloma, breast,
prostate, pancreas, colon, brain and lung cancers. It is also thought that CSCs drive the
metastatic spread of cancer. The CSC compartment features a specific and phenotypically
defined cell...
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