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The Language of Caring: Quantitating Medical Practice Patterns using Symbolic Dynamics

J. PaladinoA. M. KaynarP. S. CrookeJ. R. Hotchkiss — 2010

Mathematical Modelling of Natural Phenomena

Real-world medical decisions rarely involve binary Ðsole condition present or absent- patterns of patient pathophysiology. Similarly, provider interventions are rarely unitary in nature: the clinician often undertakes multiple interventions simultaneously. Conventional approaches towards complex physiologic derangements and their associated management focus on the frequencies of joint appearances, treating the individual derangements of physiology...

Modeling the Cancer Stem Cell Hypothesis

C. CalmeletA. ProkopJ. MensahL. J. McCawleyP. S. Crooke — 2010

Mathematical Modelling of Natural Phenomena

Solid tumors and hematological cancers contain small population of tumor cells that are believed to play a critical role in the development and progression of the disease. These cells, named Cancer Stem Cells (CSCs), have been found in leukemia, myeloma, breast, prostate, pancreas, colon, brain and lung cancers. It is also thought that CSCs drive the metastatic spread of cancer. The CSC compartment features a specific and phenotypically defined cell...

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