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We connect the theorems of Rentschler [] and Dixmier [] on locally nilpotent derivations and automorphisms of the polynomial ring $A_0$ and of the Weyl algebra $A_1$, both over a field of characteristic zero, by establishing the same type of results for the family of algebras $$A_h=\langle x,y\mid yx-xy=h\left(x\right)\rangle ,$$ where $h$ is an arbitrary polynomial in $x$. In the second part of the paper we consider a field $𝔽$ of prime characteristic and study $𝔽\left[t\right]$comodule algebra structures on $A_h$. We also compute the Makar-Limanov invariant of absolute constants...