Dynamics of simplified HPT model in relation to 24h TSH profiles
We propose a simplified mathematical model of the hypothalamus-pituitary-thyroid (HPT) axis in an endocrine system. The considered model is a modification of the model proposed by Mukhopadhyay in [9]. Our system of delay differential equations reconstructs the HPT-axis in relation to 24h profiles of human in physiological conditions. Homeostatic control of the thyroid-pituitary axis is considered by using feedback and delay in our model. The influence of delayed feedback on the stability behaviour...