The role of cell motility in metastatic cell dominance phenomenon: Analysis by a mathematical model.
Autowaves in the Model of Infiltrative Tumour Growth with Migration-Proliferation Dichotomy
A mathematical model of infiltrative tumour growth is investigated taking into account transitions between two possible states of malignant cells: proliferation and migration. These transitions are considered to depend on oxygen level in a threshold manner where high oxygen concentration allows cell proliferation, while concentration below a certain critical value induces cell migration. The infiltrative tumour spreading rate dependence on model parameters is obtained. It is shown that the tumour...
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