Displaying similar documents to “Spatial correlation of gene expression measures in tissue microarry core analysis.”

Stochastic models of progression of cancer andtheir use in controlling cancer-related mortality

Marek Kimmel, Olga Gorlova (2003)

International Journal of Applied Mathematics and Computer Science

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A construction of a realistic statistical model of lung cancer risk and progression is proposed. The essential elements of the model are genetic and behavioral determinants of susceptibility, progression of the disease from precursor lesions through early (localized) tumors to disseminated disease, detection by various modalities, and medical intervention. Using model estimates as a foundation, mortality reduction caused by early-detection and intervention programs can be predicted under...