Polymyositis, topological proteomics technology and paradigm for cell invasion dynamics.
Schubert, Walter (2002)
Journal of Theoretical Medicine
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Schubert, Walter (2002)
Journal of Theoretical Medicine
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G. Pinna, A. Zinovyev, N. Araujo, N. Morozova, A. Harel-Bellan (2012)
Mathematical Modelling of Natural Phenomena
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Many cancer-associated genes and pathways remain to be identified in order to clarify the molecular mechanisms underlying cancer progression. In this area, genome-wide loss-of-function screens appear to be powerful biological tools, allowing the accumulation of large amounts of data. However, this approach currently lacks analytical tools to exploit the data with maximum efficiency, for which systems biology methods analyzing complex...
A. Szabó, A. Czirók (2010)
Mathematical Modelling of Natural Phenomena
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Collective cell motility and its guidance via cell-cell contacts is instrumental in several morphogenetic and pathological processes such as vasculogenesis or tumor growth. Multicellular sprout elongation, one of the simplest cases of collective motility, depends on a continuous supply of cells streaming along the sprout towards its tip. The phenomenon is often explained as leader cells pulling the rest of the sprout forward via cell-cell adhesion. Building on an empirically demonstrated...