Displaying similar documents to “Mathematical and numerical analysis of a model for anti-angiogenic therapy in metastatic cancers”

Mathematical and numerical analysis of a model for anti-angiogenic therapy in metastatic cancers

Sébastien Benzekry (2012)

ESAIM: Mathematical Modelling and Numerical Analysis - Modélisation Mathématique et Analyse Numérique

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We introduce a phenomenological model for anti-angiogenic therapy in the treatment of metastatic cancers. It is a structured transport equation with a nonlocal boundary condition describing the evolution of the density of metastases that we analyze first at the continuous level. We present the numerical analysis of a lagrangian scheme based on the characteristics whose convergence establishes existence of solutions. Then we prove an error estimate and use the model to perform interesting...

Mathematical and numerical analysis of a model for anti-angiogenic therapy in metastatic cancers

Sébastien Benzekry (2011)

ESAIM: Mathematical Modelling and Numerical Analysis

Similarity:

We introduce a phenomenological model for anti-angiogenic therapy in the treatment of metastatic cancers. It is a structured transport equation with a nonlocal boundary condition describing the evolution of the density of metastases that we analyze first at the continuous level. We present the numerical analysis of a lagrangian scheme based on the characteristics whose convergence establishes existence of solutions. Then we prove an error estimate and use the model to perform interesting...

Numerical solution of a new hydrodynamic model of flocking

Kučera, Václav, Živčáková, Andrea

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This work is concerned with the numerical solution of a hydrodynamic model of the macroscopic behavior of flocks of birds due to Fornasier et al., 2011. The model consists of the compressible Euler equations with an added nonlocal, nonlinear right-hand side. As noticed by the authors of the model, explicit time schemes are practically useless even on very coarse grids in 1D due to the nonlocal nature of the equations. To this end, we apply a semi-implicit discontinuous Galerkin method...

A finite-volume scheme for a kidney nephron model

Aurélie Edwards, Nicolas Seguin, Magali Tournus (2012)

ESAIM: Proceedings

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We present a finite volume type scheme to solve a transport nephron model. The model consists in a system of transport equations with specific boundary conditions. The transport velocity is driven by another equation that can undergo sign changes during the transient regime. This is the main difficulty for the numerical resolution. The scheme we propose is based on an explicit resolution and is stable under a CFL condition which does not depend on the stiffness of source terms. ...

A mathematical model of inflammation during ischemic stroke

Cristiana Di Russo, Jean-Baptiste Lagaert, Guillemette Chapuisat, Marie-Aimée Dronne (2010)

ESAIM: Proceedings

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In this article we propose a model to describe the inflammatory process which occurs during ischemic stroke. First, an introduction to some basic concepts about the biological phenomenon is given. Then, a detailed derivation of the model and the numerical scheme used are presented. Finally, the studies of the model robustness and sensitivity are showed and some numerical results on the time and space evolution of the process are presented...

Long-Time Simulation of a Size-Structured Population Model with a Dynamical Resource

L. M. Abia, O. Angulo, J. C. López-Marcos, M. A. López-Marcos (2010)

Mathematical Modelling of Natural Phenomena

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In this paper, we study the numerical approximation of a size-structured population model whose dependency on the environment is managed by the evolution of a vital resource. We show that this is a difficult task: some numerical methods are not suitable for a long-time integration. We analyze the reasons for the failure.

Numerical schemes for a three component Cahn-Hilliard model

Franck Boyer, Sebastian Minjeaud (2011)

ESAIM: Mathematical Modelling and Numerical Analysis - Modélisation Mathématique et Analyse Numérique

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In this article, we investigate numerical schemes for solving a three component Cahn-Hilliard model. The space discretization is performed by using a Galerkin formulation and the finite element method. Concerning the time discretization, the main difficulty is to write a scheme ensuring, at the discrete level, the decrease of the free energy and thus the stability of the method. We study three different schemes and prove existence and convergence theorems. Theoretical results are illustrated...

Increasing the Calculation Speed of an Acceleration Scheme for an Age-Structured Diffusion Model Повишаване на изчислителната скорост на ускорена схема за възрастово структуриран дифузионен модел

Boyadzhiev, Doychin, Pelovska, Galena (2011)

Union of Bulgarian Mathematicians

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Дойчин Бояджиев, Галена Пеловска - В статията се предлага оптимизиран алгоритъм, който е по-бърз в сравнение с по- рано описаната ускорена (модифицирана STS) диференчна схема за възрастово структуриран популационен модел с дифузия. Запазвайки апроксимацията на модифицирания STS алгоритъм, изчислителното времето се намаля почти два пъти. Това прави оптимизирания метод по-предпочитан за задачи с нелинейност или с по-висока размерност. In this paper we propose an optimized...