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Displaying similar documents to “A simple mathematical model of the human liver”

The problem of data assimilation for soil water movement

François-Xavier Le Dimet, Victor Petrovich Shutyaev, Jiafeng Wang, Mu Mu (2004)

ESAIM: Control, Optimisation and Calculus of Variations

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The soil water movement model governed by the initial-boundary value problem for a quasilinear 1-D parabolic equation with nonlinear coefficients is considered. The generalized statement of the problem is formulated. The solvability of the problem is proved in a certain class of functional spaces. The data assimilation problem for this model is analysed. The numerical results are presented.

Identifiability and estimation of pharmacokinetic parameters for the ligands of the macrophage mannose receptor

Nathalie Verdiere, Lilianne Denis-Vidal, Ghislaine Joly-Blanchard, Dominique Domurado (2005)

International Journal of Applied Mathematics and Computer Science

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The aim of this paper is numerical estimation of pharmacokinetic parameters of the ligands of the macrophage mannose receptor, without knowing it a priori the values of these parameters. However, it first requires a model identifiability analysis, which is done by applying an algorithm implemented in a symbolic computation language. It is shown that this step can lead to a direct numerical estimation algorithm. In this way, a first estimate is computed from noisy simulated observations...

Properties of a singular value decomposition based dynamical model of gene expression data

Krzysztof Simek (2003)

International Journal of Applied Mathematics and Computer Science

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Recently, data on multiple gene expression at sequential time points were analyzed using the Singular Value Decomposition (SVD) as a means to capture dominant trends, called characteristic modes, followed by the fitting of a linear discrete-time dynamical system in which the expression values at a given time point are linear combinations of the values at a previous time point. We attempt to address several aspects of the method. To obtain the model, we formulate a nonlinear optimization...

Some tracks in air pollution modelling and simulation.

Bruno Sportisse, Jaouad Boutahar, Edouard Debry, Denis Quélo, Karine Sartelet (2002)

RACSAM

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In this article we discuss some issues related to Air Pollution modelling (as viewed by the authors): subgrid parametrization, multiphase modelling, reduction of high dimensional models and data assimilation. Numerical applications are given with POLAIR, a 3D numerical platform devoted to modelling of atmospheric trace species.

Numerical analysis of nonlinear model of excited carrier decay

Natalija Tumanova, Raimondas Čiegis, Mečislavas Meilūnas (2013)

Open Mathematics

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This paper presents a mathematical model for photo-excited carrier decay in a semiconductor. Due to the carrier trapping states and recombination centers in the bandgap, the carrier decay process is defined by the system of nonlinear differential equations. The system of nonlinear ordinary differential equations is approximated by linearized backward Euler scheme. Some a priori estimates of the discrete solution are obtained and the convergence of the linearized backward Euler method...

Sensitivity studies of pollutant concentrations calculated by the UNI-DEM with respect to the input emissions

Ivan Dimov, Raya Georgieva, Tzvetan Ostromsky, Zahari Zlatev (2013)

Open Mathematics

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The influence of emission levels on the concentrations of four important air pollutants (ammonia, ozone, ammonium sulphate and ammonium nitrate) over three European cities (Milan, Manchester, and Edinburgh) with different geographical locations is considered. Sensitivity analysis of the output of the Unified Danish Eulerian Model according to emission levels is provided. The Sobol’ variance-based approach for global sensitivity analysis has been applied to compute the corresponding sensitivity...