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Spatial dynamics of fibrin clot formation in non-stirred system activated by glass
surface was studied as a function of FIX activity. Haemophilia B plasma was obtained from
untreated patients with different levels of FIX deficiency and from severe haemophilia B patient
treated with FIX concentrate (Ahemphil B) during its clearance with half-life t=12 hours. As
reported previously (Ataullakhanov et al. Biochim Biophys Acta 1998; 1425: 453-468), clot
growth in space showed two distinct phases: activation...
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